TYPES & PRICE OF HPV VACCINE & SHORT COMINGS; you must know

Parents frequently enquire about types and price of HPV vaccines ready for use. The reason why everyone is so eager to find out more about HPV vaccine is, it is an anti-cervical cancer vaccine. 

What is HPV ?

HPV stands for “human papilloma virus”. It is main offender for cervix cancer in women. After years and years of research and diligence, vaccine has been developed against HPV. This HPV vaccine prevents not only cervix cancer in women, but also cancer of mouth and ano-genital region of males too.

How important is HPV Vaccine? Is it mandatory to take HPV vaccine ?

HPV is the most frequent sexually transmitted infection in human. By the time a person reaches 50 years age almost every person gets HPV infection.

Now talking about global burden of cervical cancer, it is the number one cause of cancer death in women in developing countries. Also it is the second leading cause of cancer in women world wide. And 100% of all cervical cancer cases have HPV infection as its root element. 

Looking at the magnitude and severity of cervix cancer in women, WHO ( World Health Organisation ) and CDC ( Centre of Disease Contributed & Prevention) recommend to vaccinate all girls and boys between 11-12 years ( 9 – 14 years being ideal age ) with HPV vaccine. Maximum age for vaccination is 45 years. 

 

IAP ( Indian Academy of Pediatrics ) approves to give HPV vaccine to all females between 9 – 14 years of age, provided parents can afford it ( baring few exceptional cases ).

To know the fundamental of how exactly HPV vaccine works and what are its side effects read our article below.

DO YOU KNOW HPV VACCINE PREVENTS WHAT KILLER CANCER ?

Is HPV vaccine meant for males too ?

Yes, absolutely it is. Now a days it is advisable for males to take HPV vaccine as well between 9 – 14 years of age, before getting exposed to the virus. This wards of ano-genital and head and neck cancer in men. Also it checks transmission of HPV infection further in community. 

What are the types of HPV vaccine ?

As a parent it is quite baffling to choose the type of  HPV vaccine for your kid. This article will put a detailed insight into all types of HPV vaccine. Before that, let us get some inherent facts about Human papilloma virus and its types. 

13 serotypes of human papilloma viruses are infamous for causing cancer in human. Type 16 and 18 are associated with majority cases of cervix cancer. Besides type 6 & 11 are also pathologically significant as they cause benign lesion like warts. Warts are nothing but growth on skin and mucus membrane. 

Till date 3 types of HPV vaccines are certified for use. 

  • Cervarix( bivalent vaccine )
  • Gardasil ( quadrivalent vaccine )
  • Gardasil 9 ( nonavalent vaccine ) 

Vaccine details

 (2vHPV / HPV 2 vaccine

This vaccine has 2 serotypes, namely 16 and 18 of HPV. Hence it is called bivalent vaccine.

(4vHPV / HPV 4 Vaccine)

This has 16 and 18 serotypes. Additionally it has serotypes 6 and 11 too.

(9vHPV / HPV 9 Vaccine)

It is a nonavalent vaccine. It gives protection from 9 serotypes of HPV. These serotypes are 6, 11, 16, 18, 31, 33, 45, 52, 58

It is compelling to note that all HPV vaccines give protection against type 16 and 18. The reason being these 2 serotypes belong to high risk categories. They contribute to around 70% of all cervical cancer cases around world. 

 

Which vaccine is better ? Which vaccine should parents prefer ?

Gardasil 9 is the most latest vaccine that gives more or less 98% protection against cervical cancer. It was licensed to use in year 2014. So far it is the best vaccine as it immunise against maximum number of serotypes. 

But at majority centres commonly available HPV vaccines are Cervarix and Gardasil ( 4vHPV or quadrivalent vaccine ). Given a choice out of these two Gardasil quadrivalent is better than Cervarix, as it protects against both warts and cancer 

For males the vaccines licensed to use in India is HPV 9 Vaccine ( Even so, here it is not mandatory in males until now ). In many other countries HPV 4 vaccine is also used for males. 

Dose of HPV Vaccine

Dose of HPV vaccine is either a 2 dose or a 3 dose schedule. Which schedule need to be followed grounds on age of a person and type of vaccine.

For Cervarix and Gardasil, it is observed that excellent amount of immunity is generated if given before 15th birthday. Hence only 2 doses are enough. 

 

But if first dose of vaccine is given one or after 15th birthday then 3 dose guideline is apt.

Below is the detailed schedule of all 3 types of vaccines 

  • 0-6/12 means first dose if given today and second dose should be given after 6 months or after 1 year of first dose.
  • 0-1-6 means first dose if given today, then second dose to be given after 1 month of first dose and 3 rd dose to be given after 6 months of first dose.
  • 0-1-6 means first dose if given today, then second dose to be given after 1 month of first dose and 3 rd dose to be given after 6 months of first dose.

One dose is 0.5 ml to give given in muscle ( intar muscular ). It’s better if the person taking vaccine is in seated or or in reclined posture. 

Price of HPV vaccine

After 2016, the only vaccine available in United States and many developed countries is Gardasil 9. The cost of which is about 250 – 400 dollars for full schedule. Verify if you have insurance that covers for HPV vaccine. 

In developing countries it is a bit cheaper. Approximate money spent to get one dose of Gardasil quadrivalent vaccine is 3900 rupees and Cervarix is 2600 rupees. If you are lucky enough to get a discount of even 10% then that’s great. These 2 vaccines are available at greater part of India currently

Cost of a dose of Gardasil 9 in India would be around 10,000 rupees. The price sounds overboard. Isn’t it. This is so because a huge amount is spent to research and to manufacture these products. 

One HPV vaccine vial contain 0.5 ml of vaccine equivalent for one single dose. After purchase make sure to keep it at 2-8 degree Celsius, and never freeze

HPV vaccine benefits

Over and above it prevents genital warts and precancerous conditions. 

This vaccine prevents not only cervix cancer in women but also head and neck, genital cancer in men. 

Shortcomings of HPV vaccine

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A woman is given HPV vaccine doesn’t mean she is excluded from cervical cancer screening test. Pap smear screening to detect cervix cancer and precancerous condition is indispensable in women irrespective of vaccine status. 

 

Important to note here is that HPV Immunization prevents chances of cancer multifold, but does not rule out its development completely.

Conclusion

Are you well informed parent now ? If yes, then share this article with other parents too. A small word of awareness goes a long way. 

Caution

 

Always consult your primary physician before taking any decision on HPV vaccination.

All the informations provided here are for educational and awareness purpose only. Kindly do not use these as alternative to medical consultation.

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